What does the literature say about the persistence of the drugs that we use by law Ricarte Soto in Rheumatoid Arthritis?

Abstract

Law No. 20,850, known as the Ricarte Soto law (LRS), has expanded the possibility of using high-cost drugs in rheumatoid arthritis (RA) in Chile. But frequently we are faced with the fact that patients do not maintain the indicated medication for the expected time, for various reasons. The persistence of a drug is the time that elapses from its inception until its interruption, and can be used as a surrogate marker of the success of the long-term treatment as it reflects clinical effectiveness, the absence of significant adverse events and satisfaction with treatment. In this article we review the persistence data for the different drugs available for RA. by LRS in Chile and we will discuss the factors that may influence it.