Extrarenal recurrence of anti-neutrophil cytoplasmic antibody associated vasculitis in a renal transplant recipient
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Keywords
Anti-neutrophil cytoplasmic antibody-associated vasculitis, kidney transplantation, recurrence, rituximab
Abstract
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic autoimmune disease characterized by inflammation of small blood vessel walls, often involving the kidneys. Although the prognosis has improved, up to 40% of patients may develop end-stage chronic kidney disease (ESKD). Renal transplantation is the treatment of choice in these cases, as it is associated with reduced mortality. Although disease relapse post-transplant is rare, cases with various clinical manifestations and therapeutic approaches have been documented. We report the case of a patient with a late extrarenal relapse of ANCA, vasculitis, successfully treated with rituximab.
References
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